The Clock Interaction report analyzes timing paths that cross from one clock domain (the source clock) into another clock domain (the destination clock). The Clock Interaction report helps to identify cases in which there may be data loss or metastability issues.
After you run the Report Clock Interaction command, the results open in the Clock Interaction window. As shown in the following figure, the Clock Interaction Report displays as a matrix of clock domains with the source clocks in the vertical axis and the destination clocks in the horizontal axis.
Figure 1. Report Clock Interaction