The Manage IP button opens the IP Manager dialog box, allowing you to run IP Module wizards to easily enter various types of external memory interfaces (e.g, DDR4, DDR3, DDR3L, LPDDR2, QDR+, RLDRAM), transceiver based interfaces (e.g, 10GBASE-R, Interlaken, PCIe, Aurora, CPRI and many more), and block memory or distributed memory.
For a description of the IP_Manager wizard, see Using IP Module Wizards.