For simplex configurations, because the TX and RX can be powered on independently, data transmission must begin only after rx_channel_up is seen (that is, after a minimum of 45 ms of tx_channel_up ), to avoid loss of data., Before asserting pma_init , the reset_pb must be asserted for a minimum time equal to 128* user_clk time period to ensure that the portion of the core in programmable logic goes to a known reset state before the user_clk is held Low during pma_init assertion. The assertion time of pma_init must be a minimum of six INIT_CLK cycle time period to satisfy the requirements of the core de-bouncing circuit.