In Vitis Model Composer you can use cross probing between the signal in the AMD Waveform Viewer and the Simulink diagram to aid the debugging process.
To add a signal to the Waveform viewer, right-click the signal in the model and select AMD Add To Viewer. Simulating the design should launch the Waveform Viewer as shown below.
Figure 1. Waveform Viewer
All signals in same clock domain are colored similarly. In the
figure above: src_domain/Slice/Out1 and
dest_domain/Relational/Out1 are in different clock
domains.